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Thursday November 11

8.15

Welcome and Introduction
Joseph Buxbaum

Session 1 - Genetics and genomics of Autism spectrum disorders
Chair: J. Buxbaum, Mount Sinai School of Medicine, USA

8.30

O1- Autism spectrum disorders: behavioral manifestations of numerous genetic disorders
C. Betancur, INSERM U952, Université Pierre et Marie Curie, France

9.00

O2- The genomic architecture in Autism spectrum disorder
S. Scherer, The Hospital for Sick Children, The university of Toronto, Canada

9.30

O3- TBC
B. Devlin, UPMC, USA

10.00

O4- Next-generation sequencing in autism spectrum disorders
J. Buxbaum, Mount Sinai School of Medicine, USA

10.30

Coffee Break

Session 2: Animal models of Autism spectrum disorders
Chair: J. Crawley, NIMH, USA

11.00

O5- Behavioral phenotyping strategies for genetic mouse models of Autism
J. Crawley, NIMH, USA

11.30

O6- Using a Drosophila model to investigate the underlying causes of symptoms associated with fragile X syndrome
T. Jongens, University of Pennsylvannia, USA

12.00

O7- Haploinsufficiency of Shank3 leads to neuronal deficits in a mouse model of Phelan-McDermid syndrome
J. Buxbaum, Mount Sinai School of Medicine, USA

12.30

O8- Adult reversal of neurodevelopmental disorders: Impact on autism
A. Silva, University of California at Los Angeles, USA

1.00

Lunch

Session 3: Changes in brain growth and function from infancy to adulthood in Autism
Chair: E. Courchesne, University of California at San Diego, USA

2.00

O9- Structural defects that underlie autism: Overgrowth in the first years of life followed by arrest and degeneration
E. Courchesne, University of California at San Diego, USA

2.30

O10- Early Neurofunctional Signatures of Autism between 12 and 36 months
K. Pierce, University of California at San Diego, USA

3.00

O11- The neurobiology of Autism in adulthood
D. Murphy, Institute of Psychiatry, Kings College London, UK

3.30

Coffee Break

Session 4: Research into the neuropathology of Autism
Chair: D. Amaral, University of California at Davis, USA

4.00

O12- Atypical cytoarchitecture in the amygdala and temporal cortex in autism
C. Schumann, University of California at Davis, USA

4.30

O13- Regionally discrete and cell type-specific neocortical neuronal pathology in autism
P. Hof, Mount Sinai School of Medicine, USA

5.00

O14- Alterations in the GABAergic system in the Autism brain: Emerging evidence for widespread defects in cerebellar, limbic and cortical regions
G. Blatt, Boston University School of Medicine, USA

5.30

O15- Molecular neuropathology in ASD: clues in pathogenesis
C. Pardo, Johns Hopkins University School of Medicine, USA

6.00

Poster reception

Friday November 12

Session 5: Understanding the behaviors in ASD that brain approaches are attempting to explain
Chair: C. Lord, University of Michigan Autism and Communication Disorders Center, USA

9.00

O16- Does understanding the cognitive phenotype help us in understanding the behavioral phenotype of autism?
T. Charman, Institute of Education, University of London, UK

9.30

O17- Beyond recognition: face processing abnormalities in young children with ASD
K. Chawarska, Yale University, USA

10.00

O18- Trajectories and dimensions in behavioral features of ASD
C. Lord, University of Michigan Autism and Communication Disorders Center, USA

10.30

Coffee Break

Session 6: Cutting edge research in behavioral interventions for ASD
Chair: S. Rogers, University of California Davis Medical Center

11.00

O19- Parent-assisted children’ friendship training for children with high functioning Autism spectrum disorders
F. Frankel, University of California at Los Angeles, USA

11.30

O20- Towards a technology of treatment individualization for young children with Autism
A. Stahmer, The Child and Adolescent Services Research Center , USA

12.00

O21- Group cognitive behavior therapy for children and adolescents with high-functioning Autism spectrum disorders and anxiety
J. Reaven, University of Colorado School of Medicine, USA

12.30

O22- Developing treatments for infants and toddlers with autism
S. Rogers, University of California Davis Medical Center

1.00

Lunch

Session 7: Pharmacological interventions for Autism spectrum disorders
Chair: C. McDougle, Indiana University School of Medicine, USA

2.00

O23- Pharmacotherapy of irritability in Autism spectrum disorders
C. McDougle, Indiana University School of Medicine, USA

2.30

O24- Pharmacotherapy of hyperactivity and repetitive behaviors in autism spectrum disorders
B. King, University of Washington, USA

3.00

O25- Developing drugs for core social and communication impairment in Autism
C. Erickson, MD, Indiana University School of Medicine , USA

3.30

Coffee Break

Session 8: Plenary session

4.00

PLENARY PRESENTATION
D. Amaral, University of California at Davis, USA

4.45

Closing remarks